C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 263/10 (2006.01) A61K 31/422 (2006.01) A61P 7/02 (2006.01) C07D 263/20 (2006.01) C07D 295/22 (2006.01)
Patent
CA 2393217
Compounds of formula (I), wherein R1, R2 and n have the meanings give in claim N~1, and their physiologically compatible salts and solvates can be used as GP IIbIIIa antagonists for combating thromboses, osteoporosis, oncosis, apoplexy, cardiac infarction, ischemia, infections, arteriosclerosis and osteolytic diseases.
Selon l'invention, les composés de la formule (I) dans laquelle R?1¿, R?2¿ et n ont la signification indiquée dans la revendication 1, et leurs sels et solvates physiologiquement acceptables, peuvent être utilisés en tant qu'antagonistes de GP IIbIIIa pour la lutte contre les thromboses, l'ostéoporose, les maladies tumorales, l'apoplexie, l'infarctus du myocarde, l'ischémie, les inflammations, l'artériosclérose, et les maladies ostéolytiques.
Barnes Christopher
Buhring Karl-Ulrich
Dasenbrock Johannes
Goodman Simon
Tsaklakidis Christos
Astellas Pharma Inc.
Fetherstonhaugh & Co.
Merck Patent Gesellschaft Mit Beschraenkter Haftung
Yamanouchi Pharmaceutical Co. Ltd.
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