A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/18 (2006.01) A61K 38/00 (2006.01) A61K 38/19 (2006.01) A61K 38/30 (2006.01) C12Q 1/02 (2006.01)
Patent
CA 2249666
Methods for treating gastrointestinal tract disorders by protection, regeneration and repair of intestinal epithelium are described. Macrophage stimulating protein is found to promote colony formation by crypt cells and may be involved in stimulating proliferation of intestinal crypt cells. Also described are pharmaceutical compositions for MSP and methods for identifying substances that stimulate crypt cell proliferation.
L'invention concerne des procédés utilisés pour traiter des troubles du tractus gastro-intestinal par la protection, la régénération et la réparation de l'épithélium intestinal. La protéine de stimulation de macrophages stimule la formation de colonies par des cellules cryptiques et peut participer à la stimulation de la prolifération de cellules cryptiques intestinales. L'invention concerne également des compositions pharmaceutiques à base de protéine de stimulation de macrophages et des procédés servant à identifier des substances stimulant la prolifération de cellules cryptiques.
Amgen Inc.
Gowling Lafleur Henderson Llp
LandOfFree
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