Gfats as modifiers of the axin pathway and methods of use

Details Gfats as modifiers of the axin pathway and methods of use Gfats as modifiers of the axin pathway and methods of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A01N 31/00 (2006.01) A01N 61/00 (2006.01) C12N 15/00 (2006.01) G01N 33/00 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2612143

Human GFAT genes are identified as modulators of the Axin pathway, and thus are therapeutic targets for disorders associated with defective Axin function. Methods for identifying modulators of Axin, comprising screening for agents that modulate the activity of GFAT are provided.

Les gènes GFAT humains sont identifiés comme modulateurs de la voie de l'axine, et sont ainsi des cibles thérapeutiques de troubles liés à une fonction défectueuse de l'axine. L'invention concerne également des procédés d'identification de modulateurs de l'axine, comportant le criblage d'agents qui modulent l'activité de GFAT .

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