C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/90 (2006.01) A61K 31/404 (2006.01) A61K 31/4164 (2006.01) A61K 31/4245 (2006.01) A61K 31/5383 (2006.01) A61K 31/542 (2006.01) A61P 13/00 (2006.01) C07D 209/14 (2006.01) C07D 233/54 (2006.01) C07D 233/56 (2006.01) C07D 233/92 (2006.01) C07D 233/94 (2006.01) C07D 403/06 (2006.01) C07D 413/04 (2006.01) C07D 498/04 (2006.01) C07D 513/14 (2006.01)
Patent
CA 2430696
This invention relates to the use of compounds of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in the description, A signifies -CH=CH- or -C=C-; and B signifies (B1); (B2); (B3); (B4); (B5) or (B6); wherein R6 to R26, X and Y have the significances given in the description, as well as pharmaceutically acceptable salts thereof, for the manufacture of medicaments for the treatment or prevention of mGluR5 receptor mediated disorders.
L'invention concerne l'utilisation de composés de la formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et R?5¿ possèdent la signification donnée dans le descriptif ; A est -CH=CH- ou -C=C- ; B est B1), B2), B3), B4), B5) ou B6) ; et R?6¿ à R?26¿, et X et Y possèdent la signification donnée dans le descriptif, ainsi que l'utilisation des sels pharmaceutiquement acceptables desdits composés dans la fabrication de médicaments destinés au traitement ou à la prévention de maladies liées au récepteur de mGluR5.
Mutel Vincent
Peters Jens-Uwe
Wichmann Juergen
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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