Spiro-substituted azacycles as neurokinin-3 antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 211/14 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) C07D 211/34 (2006.01) C07D 211/58 (2006.01) C07D 213/74 (2006.01) C07D 213/75 (2006.01) C07D 221/20 (2006.01) C07D 295/145 (2006.01) C07D 295/15 (2006.01) C07D 471/10 (2006.01) C07D 495/10 (2006.01)

Patent

CA 2188031

Disclosed are spiro-substituted azacycles of formula (I) as selective neurokinin-3 antagonists useful in the treatment of CNS disorders.

Azacycles spiro-substitués représentés par la formule (I) et efficaces, en tant qu'antagonistes sélectifs de neurokinine-3, pour traiter des maladies du système nerveux central.

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