C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/435 (2006.01) C07K 14/705 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/62 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2604925
Multivalent soluble receptor proteins that bind to more than one angiogenic factor are described. Nucleotide and vector sequences which encode the multivalent soluble receptor protein, as well as host cells which comprise them and methods of making and using them are also described. The multivalent soluble receptor proteins and vectors which encode them find utility in treatment of cancer and other diseases associated with angiogenesis.
L'invention concerne des protéines de récepteurs solubles polyvalentes se liant à plus d'un facteur angiogène. L'invention concerne également des séquences nucléotidiques et de vecteurs codant la protéine de réception soluble polyvalente et les cellules hôtes les contenant ainsi que leurs procédés de préparation et d'utilisation. Les protéines de réception solubles et polyvalentes de même que les vecteurs les codant trouvent une application dans le traitement du cancer et d'autres maladies associées à l'angiogenèse.
Harding Thomas
Nguyen Minh
Cell Genesys Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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