C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/45 (2006.01) A61K 39/145 (2006.01) A61K 39/17 (2006.01) C12N 5/10 (2006.01) C12N 15/00 (2006.01) C12N 15/44 (2006.01) C12N 15/82 (2006.01)
Patent
CA 2524293
The invention is drawn towards vectors and methods useful for preparing genetically transformed plant cells that express immunogens from pathogenic organisms which are used to produce immunoprotective particles useful in vaccine preparations. The invention includes plant optimized genes that encode the HN protein of Newcastle Disease Virus. The invention also relates to methods of producing an antigen in a transgenic plant.
L'invention concerne des vecteurs et des procédés utilisés pour préparer des cellules végétales génétiquement modifiées exprimant des immunogènes issus d'organismes pathogènes utilisés pour produire des particules immunoprotectrices utilisées dans des préparations de vaccins. L'invention concerne également des gènes végétaux optimisés codant la protéine HN du virus de la maladie de Newcastle. L'invention concerne également des procédés permettant de produire un antigène dans un végétal transgénique.
Cardineau Guy A.
Kirk Dwayne D.
Mason Hugh Stanley
Vaneck Joyce M.
Walmsley Amanda Maree
Boyce Thompson Institute For Plant Research
Dow Agrosciences Llc
Torys Llp
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