Novel methods of diagnosis of angiogenesis compostions and...

G - Physics – 01 – N

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G01N 33/50 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01)

Patent

CA 2381699

Described herein are methods that can be used for diagnosis of angiogenesis and angiogenic phenotypes. Also described herein are methods that can be used to screen candidate bioactive agents for the ability to modulate angiogenesis. Additionally, methods and molecular targets (genes and their products) for therapeutic intervention in disorders associated with angiogenesis are described.

L'invention concerne des techniques pouvant s'utiliser pour diagnostiquer l'angiogénèse et les phénotypes angiogéniques. L'invention concerne également des techniques pouvant s'utiliser pour cribler des agents bioactifs candidats, afin de moduler l'angiogénèse. Elle concerne, en outre, des techniques et des cibles moléculaires (gènes et leurs produits) permettant une intervention thérapeutique dans des troubles associés à l'angiogénèse.

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