Pharmaceuticals comprising n,n'-bis(2- hydroxybenzyl)...

Details Pharmaceuticals comprising n,n'-bis(2- hydroxybenzyl)... Pharmaceuticals comprising n,n'-bis(2- hydroxybenzyl)...

C - Chemistry, Metallurgy

07

C

C07C 229/06 (2006.01) A61K 9/08 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01)

Patent

CA 2319255

The use of N,N'-bis(2- hydroxybenzyl) ethylenediamine-N, N'-diacetic acid (HBED) in iron chelating therapy is disclosed. In particular, the invention relates to the subcutaneous use of HBED for treating mammals with a disease treatable by an iron chelator such as iron overload, especially transfusional iron overload.

L'invention concerne l'utilisation de l'acide N,N'-bis(2- hydroxybenzyl) éthylènediamine-N, N'-diacétique (HBED) dans le traitement par chélation du fer. Elle concerne en particulier l'utilisation sous-cutanée de l'HBED pour traiter les mammifères atteints d'une maladie pouvant être traitée par un chélateur du fer, telle qu'une surcharge en fer, notamment une surcharge en fer post-transfusionnelle.

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