Prodrugs of cox-2 inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 261/08 (2006.01) A61K 9/48 (2006.01) A61K 31/415 (2006.01) A61K 31/42 (2006.01) A61K 31/422 (2006.01) A61K 31/635 (2006.01) A61K 31/7056 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01) C07D 231/12 (2006.01) C07D 413/12 (2006.01) C07H 13/00 (2006.01) A61K 47/02 (2006.01) A61K 47/12 (2006.01) A61K 47/22 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2444267

A compound of Formula (I), or a pharmaceutically-acceptable salt thereof, suitable for use in the treatment of a cyclooxygenase-2 mediated disease is provided. Also provided is a pharmaceutical composition comprising a compound of Formula (I), or a pharmaceutically-acceptable salt thereof, and a method for treatment of a cyclooxygenase-2 mediated disease by administering to a subject in need thereof a therapeutically-effective amount of the pharmaceutical composition.

L'invention concerne un composé représenté par la formule (I) ou un sel de celui-ci pharmaceutiquement acceptable approprié pour traiter une maladie induite par une cyclooxygénase-2. L'invention concerne également une composition pharmaceutique comprenant le composé représenté par la formule (I) ou un sel de celui-ci pharmaceutiquement acceptable, et une méthode permettant de traiter une maladie induite par une cyclooxygénase-2 par administration à un sujet qui a besoin d'un tel traitement d'une quantité thérapeutiquement efficace de ladite composition pharmaceutique.

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