Methods for cultivating lawsonia intracellularis

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 5/00 (2006.01) A61K 39/106 (2006.01) C12N 1/20 (2006.01) C12N 1/38 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2586093

This invention relates to methods for cultivating Lawsonia intracellularis. In particular, the present invention provides improved methods for cultivating Lawsonia intracellularis by employing reducing agents other than molecular hydrogen; or alternatively, by employing a combination of one or more reducing agents with molecular hydrogen. This invention also relates to vaccines and diagnostic reagents prepared from Lawsonia intracellularis cultivated by employing the methods disclosed herein.

Procédés de culture de Lawsonia intracellularis. Plus particulièrement, procédés améliorés de culture de Lawsonia intracellularis faisant intervenir des agents réducteurs autres que l'hydrogène moléculaire; ou selon une variante, faisant intervenir une combinaison d'un ou plusieurs agents réducteurs avec hydrogène moléculaire. Vaccins et réactifs diagnostiques préparés à partir de Lawsonia intracellularis cultivé selon les procédés de cette invention.

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