G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/553 (2006.01) C12Q 1/00 (2006.01) G01N 27/327 (2006.01) G01N 27/416 (2006.01) G01N 33/543 (2006.01) G01N 33/563 (2006.01)
Patent
CA 2226273
Electrode membrane combinations for use in biosensors to detect analytes in a sample and methods for making and storing same are disclosed. In one aspect, a method is provided for producing a first layer electrode membrane comprising: (1) forming a solution containing linker Lipid A, the disulfide of mercaptoacetic acid (MAAD) or similar molecule, linker Gramicidin B, membrane spanning lipid C (MSL-C) and membrane spanning lipid D (MSL-D) or other suitable linker molecules and other ion channel combinations; (2) contacting an electrode containing a clean gold surface with the solution, the disulfide containing components in the solution thus adsorbing onto the gold surface of the electrode; (3) rinsing the electrode with a suitable organic solvent; and (4) removing the excess organic solvent used for rinsing.
Braach-Maksvytis Vijoleta Lucija
Cornell Bruce
King Lionel George
Pace Ronald John
Raguse Burkhard
Ambri Limited
Australian Membrane And Biotechnology Research Institute
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
The University Of Sydney
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