Process for preparing quinolone and naphthyridone carboxylic...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) C07D 209/52 (2006.01) C07D 215/56 (2006.01) C07D 401/04 (2006.01) C07D 471/06 (2006.01) C07D 498/06 (2006.01)

Patent

CA 2278845

Antibacterial quinolone carboxylic acids and naphthyridone carboxylic acids, having an external amino group attached to their 7-substituent are prepared without the use, and subsequent removal, of blocking groups on the external amino group. In a preferred embodiment, the naphthyridone carboxylic acid is the antibiotic trovafloxacin.

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