Multi-component biological transport systems

Details Multi-component biological transport systems Multi-component biological transport systems

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A61K 47/42 (2006.01) A61K 49/00 (2006.01) C07K 14/16 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2558379

Compositions and methods are provided that are useful for the delivery, including transdermal delivery, of biologically active agents, such as non- protein non-nucleotide therapeutics and protein-based therapeutics excluding insulin, botulinum toxins, antibody fragments, and VEGF. The compositions and methods are particularly useful for topical delivery of antifungal agents and antigenic agents suitable for immunization. Alternately, the compositions can be prepared with components useful for targeting the delivery of the compositions as well as imaging components.

L'invention concerne des compositions et des méthodes utilisées pour effectuer une distribution, notamment une distribution transdermique d'agents biologiquement actifs, tels que des agents thérapeutiques non protéiques et non nucléotidiques et des agents thérapeutiques à base de protéine à l'exclusion de l'insuline, de toxines botuliques, des fragments d'anticorps et de VEGF. Lesdites compositions et méthodes sont particulièrement utiles pour effectuer une distribution topique d'agents antifongiques et d'agents antigènes appropriés pour une immunisation. Dans un autre mode de réalisation, les compositions peuvent être préparées à l'aide de composants utilisés pour cibler la distribution des compositions ainsi que des composants d'imagerie.

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