Method of providing neuroprotection using substituted...

A - Human Necessities – 61 – K

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A61K 31/409 (2006.01) A61P 9/10 (2006.01) C07D 487/22 (2006.01)

Patent

CA 2762474

Described herein are methods of treating ischemic injury comprising administering to a subject in need thereof a therapeutically effective amount of a substituted porphyrin compound. Also disclosed are methods of providing neuroprotection, methods of treating subarachnoid hemorrhage, methods of treating traumatic brain injury and methods of treating spinal cord injury using substituted porphyrins.

La présente invention concerne des méthodes de traitement de lésion ischémique comprenant l'administration, à un sujet en ayant besoin, d'une quantité efficace thérapeutiquement d'un composé de porphyrine substituée. L'invention porte en outre sur des méthodes consistant à fournir une neuroprotection, sur des méthodes de traitement d'hémorragie méningée, sur des méthodes de traitement de lésion cérébrales traumatiques, et sur des méthodes de traitement de lésion de la moelle épinière au moyen de porphyrines substituées.

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