Membrane virus host range mutations and their uses as...

Details Membrane virus host range mutations and their uses as... Membrane virus host range mutations and their uses as...

C - Chemistry, Metallurgy

12

N

C12N 7/04 (2006.01)

Patent

CA 2392235

The present invention is directed to genetically engineered, membrane- enveloped viruses with deletion mutations in the protein transmembrane domains. Also provided are viral vaccines based on the engineered viruses, methods of producing and using such vaccines.

La présente invention concerne des virus issus du génie génétique et enveloppés d'une membrane, possédant des mutations de délétion dans les domaines de protéine transmembranaire. L'invention concerne également des vaccins antiviraux basés sur les virus mis au point par génie génétique et des procédés de production et d'utilisation de ces vaccins.

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