Quinoline derivatives as 5ht5a receptor antagonists

Details Quinoline derivatives as 5ht5a receptor antagonists Quinoline derivatives as 5ht5a receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 215/38 (2006.01) A61K 31/4709 (2006.01) A61K 31/506 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2699697

The present invention relates to 2-Aminoquinoline derivatives which are represented by the general formula I wherein R1, R2 and R3 are as defined in the specification as 5-HT5A receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments.

La présente invention concerne des dérivés de 2-aminoquinoline qui sont représentés par la formule générale I dans laquelle R1, R2 et R3 sont tels que définis dans la description, utilisés comme antagonistes du récepteur 5-HT5A, leur fabrication, les compositions pharmaceutiques les contenant et leur utilisation comme médicaments.

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