Enriched antibody for detecting mycobacterial infection,...

Details Enriched antibody for detecting mycobacterial infection,... Enriched antibody for detecting mycobacterial infection,...

C - Chemistry, Metallurgy

07

K

C07K 16/12 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2574432

Enriched antibody population, highly specific for an antigen of a surface polysaccharide from a mycobacterium. In a related embodiment, the antibody is enriched by having been raised in an environment that maintains antigenically active antigen. These antibodies may be used in an immunoreactive environment for detecting the presence of a mycobacterial infection in a sample from a subject.

La présente invention concerne une population d'anticorps enrichi, hautement spécifique à un antigène d'un polysaccharide de surface provenant d'une mycobactérie. Dans un mode de réalisation associé, l'anticorps est enrichi en ce qu'il est élevé dans un environnement qui conserve un antigène antigéniquement actif. Ces anticorps peuvent être utilisés dans un environnement immunoréactif afin de détecter la présence d'une infection mycobactérienne dans un échantillon provenant d'un sujet.

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