Methods of producing a library and methods of selecting...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/63 (2006.01) C12N 15/10 (2006.01)

Patent

CA 2405499

The present invention relates to a high efficiency method of introducing DNA into linear DNA viruses such as poxvirus, a method of producing libraries in linear DNA viruses such as poxvirus, and methods of selecting polynucleotides of interest based on cell nonviability or other phenotypes.

La présente invention concerne une méthode hautement efficace d'introduction d'ADN dans des virus d'ADN tels qu'un poxvirus, une méthode de production de bibliothèques dans des virus d'ADN linéaire tels qu'un poxvirus, ainsi que des méthodes de sélection de polynucléotides d'intérêt sur la base de la non-viabilité cellulaire ou d'autres phénotypes.

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