Thiazole-substituted benzyl alcohols as leukotriene antagonists

C - Chemistry – Metallurgy – 07 – D

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C07D 277/20 (2006.01) A61K 31/425 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) C07D 277/24 (2006.01) C07D 277/26 (2006.01) C07D 277/60 (2006.01) C07D 277/64 (2006.01) C07D 417/00 (2006.01) C07D 417/10 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2132724

2132724 9321168 PCTABScor01 Compounds having formula (I) are antagonists of the actions of leukotrienes. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

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