A truncated form of the hiv p17 protein

Details A truncated form of the hiv p17 protein A truncated form of the hiv p17 protein

A - Human Necessities

61

K

A61K 39/21 (2006.01) C07K 14/16 (2006.01)

Patent

CA 2711930

The invention relates to a truncated form of the HIV-1 p17 protein, designated as AT96, which consists of the residues from 1 to 96 of the full-length p17 protein, as well as the corresponding nucleic acid sequences. The truncated AT96 protein has the same immunological features as the full-length p17 protein but at the same time is devoid of the typical detrimental biological activities of the HIV-1 p17 protein.

L'invention concerne une forme tronquée de la protéine p17 du VIH-1, appelée AT96, constituée par les résidus 1 à 96 de la protéine p17 pleine longueur, ainsi que les séquences d'acides nucléiques correspondantes. La protéine AT96 tronquée présente les mêmes caractéristiques immunologiques que la protéine p17 pleine longueur mais ne présente pas les activités biologiques néfastes typiques de la protéine p17 du VIH-1.

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