Phenyl glyoxamides as spla2 inhibitors

Details Phenyl glyoxamides as spla2 inhibitors Phenyl glyoxamides as spla2 inhibitors

C - Chemistry, Metallurgy

07

F

C07F 9/02 (2006.01) A61K 31/165 (2006.01) A61K 31/195 (2006.01) A61K 31/24 (2006.01) A61K 31/66 (2006.01) C07C 59/40 (2006.01) C07C 59/48 (2006.01) C07C 59/64 (2006.01) C07C 59/84 (2006.01) C07C 62/30 (2006.01) C07C 63/33 (2006.01) C07C 65/03 (2006.01) C07C 229/00 (2006.01) C07C 233/00 (2006.01) C07C 235/00 (2006.01) C07C 235/78 (2006.01) C07C 237/00 (2006.01) C07C 239/00 (2006.01) C07C 321/00 (2006.01) C07C 323/00 (2006.01) C07C 381/00 (2006.01) C07F 9/28 (2006.01) C07F 9/38 (2006.01) C07F 9/40 (2006.01)

Patent

CA 2274019

A class of novel phenyl glyoxamides is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

Cette invention concerne une nouvelle classe de phényl glyoxamides ainsi que l'utilisation de ces composés pour inhiber la libération d'acides gras par l'intermédiaire de sPLA¿2? pour traiter des pathologies telles que le choc septique.

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