Methods of selecting stem cells and uses thereof

Details Methods of selecting stem cells and uses thereof Methods of selecting stem cells and uses thereof

A - Human Necessities

61

K

A61K 35/14 (2006.01) C12N 5/00 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2653881

A method of selecting stem cells from a heterogeneous population of cells is disclosed. The method comprises contacting the population of cells with an apoptosis inducing agent under conditions which are apoptotic to non-stem cells and non-apoptotic to stem cells, thereby selecting the stem cells from the heterogeneous population of cells. The selected stem cells may then be used for a variety of applications including transplantation and differentiation.

La présente invention concerne un procédé de sélection de cellules souches à partie d'une population hétérogène de cellules. Le procédé comprend la mise en contact de la population de cellules avec un agent induisant l'apoptose dans des conditions qui sont apoptotiques à des cellules qui ne sont pas des cellules souches et non apoptotiques à des cellules souches permettant ainsi la sélection des cellules souches parmi la population hétérogène de cellules. Les cellules sélectionnées peuvent ensuite être utilisées pour diverses applications comprenant la transplantation et la différenciation.

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