Enhanced secretion/retention of growth hormone releasing...

Details Enhanced secretion/retention of growth hormone releasing... Enhanced secretion/retention of growth hormone releasing...

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 48/00 (2006.01) C07K 14/60 (2006.01) C07K 19/00 (2006.01) C12N 15/18 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2595619

One aspect of the current invention is a method designing and using species- specific or synthetic signal peptides and GHRH sequences for the purpose of preventing and/ or treating chronic illness in a subject by utilizing methodology that administers a single dose of nucleic acid expression vector or nucleic acid expression construct encoding a GHRH or functional biological equivalent to a subject through a parenteral route of administration.

L'invention concerne un procédé de conception et d'utilisation de peptides signal spécifiques de l'espèce ou synthétiques et de séquences de somatostatine à des fins de prévention et de traitement de maladies chroniques chez un sujet, par administration d'une dose individuelle d'un vecteur d'expression d'acides nucléiques ou d'une construction d'expression d'acides nucléiques codant une stomatostatine ou un équivalent biologique fonctionnel, à un sujet, par voie d'administration parentérale.

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