Novel antibodies

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12N 15/13 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2698609

The present invention relates to the use of VEGF antagonists and a novel anti-a5ß1 antibody for treating cancer and inhibiting angiogenesis and/or vascular permability, including inhibiting abnormal angiogenesis in diseases. The present invention also relates to compositions and kits comprising novel anti-a5ß1 antibodies and methods of making and using them.

La présente invention concerne l'utilisation d'antagonistes du VEGF et un nouvel anticorps anti-a5ß1 pour traiter le cancer et inhiber l'angiogenèse et/ou la perméabilité vasculaire, y compris pour inhiber l'angiogenèse anormale dans des maladies. La présente invention concerne également des compositions et des kits comprenant de nouveaux anticorps anti-a5ß1 et des procédés pour les fabriquer et les utiliser.

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