C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
195/1.12, 150/8.
C07H 21/00 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2026280
A format for hybridization capture of PCR amplified DNA on a solid support is provided. After labelling the amplified target DNA with biotin during amplification, the labelled DNA is specifically captured by base-pair hybridization to an amplicon-specific oligonucleotide capture probe which is bound to a solid support and the labeled DNA is detected with a biotin dependent chromogenic detection assay. In a specific format selected primers and probes are disclosed which enable the detection of Chlamydia trachomatis.
Longiaru Mathew
Silver Sheryl Beth
Sulzinski Michael Anthony
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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