Lipoxin compounds and their use in treating cell...

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 59/42 (2006.01) A61K 31/202 (2006.01) A61K 31/23 (2006.01) A61K 31/232 (2006.01) A61K 31/60 (2006.01) C07C 69/732 (2006.01) C07C 69/736 (2006.01) C07F 7/08 (2006.01)

Patent

CA 2265708

Compounds having the active site of natural lipoxins, but a longer tissue half- life are disclosed. In particular, 15-epi-lipoxins and their use in ameliorating undesired cell proliferation, which characterizes diseases such as cancer, are also disclosed.

Cette invention se rapporte à des composés comprenant le site actif des lipoxines naturelles, tout en ayant cependant une demi-vie plus longue dans les tissus. Cette invention se rapporte en particulier à des 15-épi-lipoxines et à leur utilisation pour combattre la prolifération cellulaire non désirée, qui caractérise les maladies telles que le cancer.

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