Pre-filled syringe drug delivery system

Details Pre-filled syringe drug delivery system Pre-filled syringe drug delivery system

A - Human Necessities

61

M

A61M 5/19 (2006.01) A61M 5/28 (2006.01) A61M 5/315 (2006.01) A61M 5/31 (2006.01) A61M 5/50 (2006.01)

Patent

CA 2215912

A drug delivery system includes first drug (110) and second diluent (182) syringe assemblies which are respectively pre-filled with a drug concentrate and a liquid diluent. The diluent syringe assembly is positionable in operative association within a sterility maintenance sleeve (150) of the first syringe assembly so that the assemblies are joined in fluid communication. This fluid transfer connection permits the diluent to be transferred from the second syringe assembly into a sterile mixing chamber defined by a reciprocable stopper (134) in the first syringe assembly. Thereafter, the second syringe assembly can be moved with respect to the barrel of the first syringe assembly so that the resulting mixture can be delivered for patient administration.

Un système d'administration de médicament comprend un premier ensemble seringue (110) de médicament et un second ensemble seringue (182) de diluent respectivment préremplis d'un concentré de médicament et d'un diluent liquide. L'ensemble seringue de diluent est positionnable en association fonctionnelle à l'intérieur d'un manchon (150) de conservation de stérilité du premier ensemble seringue, de sorte que les ensembles sont unis en communication fluidique. La connexion de transfert de fluide permet le transfert du diluent du second ensemble seringue jusque dans une chambre de mélange stérile définie par une butée (134) capable d'un va-et-vient, dans le premier ensemble seringue. Ensuite, le second ensemble seringue peut être déplacé par rapport au cylindre du premier ensemble seringue, de sorte que le mélange obtenu peut être libéré afin d'être administré à un patient.

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