Use of benzo-fused heterocycle sulfamide derivatives as...

A - Human Necessities – 61 – K

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A61K 31/357 (2006.01) A61K 31/353 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2634088

The present invention is a methods for neuroprotection, for treating an acute neurodegenerative disorder, for treating a chronic neurodegenerative disorder and / or for preventing neuron death or damage following brain, head and / or spinal cord trauma or injury comprising administering to a subject in need thereof a therapeutically effective amount of one or more novel benzo-fused heterocycle sulfamide derivatives of formula (I) and formula (II) as herein defined.

La présente invention concerne des procédés de protection du système nerveux destinés au traitement d'une maladie dégénérative aiguë du système nerveux, au traitement d'une maladie dégénérative chronique du système nerveux et/ou à la prévention de la mort neuronale ou des lésions consécutives aux traumatismes ou aux lésions du cerveau, de la tête et/ou de la moelle épinière. Lesdits procédés comprennent l'administration à un sujet qui en a besoin d'une quantité thérapeutiquement efficace d'un ou de plusieurs dérivés de sulfamide innovants à hétérocycle fusionné à un groupe benzo, de formule (I) ou de formule (II) telles que définies ici.

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