Process for the enantioselective enzymatic reduction of...

C - Chemistry – Metallurgy – 12 – P

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C12P 7/04 (2006.01)

Patent

CA 2697038

A process for the enantioselective enzymatic reduction of a keto compound of general formula (I), wherein R may represent any protective group for amino functions (tert. butyloxycarbonyl group (BOC), benzyloxycarbonyl group, 9-fluorenylmethoxycarbonyl group) and X= -Cl, -CN, -OH, Br, F.

L'invention concerne un procédé de réduction enzymatique énantiosélective d'un composé céto de formule générale I dans laquelle R peut représenter un groupe protecteur quelconque pour les fonctions amino (groupe tert.-butyloxycarbonyle (BOC), groupe benzyloxycarbonyle, groupe 9-fluorénylméthoxycarbonyle) et X = -Cl, -CN, -OH, Br, F.

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