Antibody to latent membrane proteins and uses thereof

Details Antibody to latent membrane proteins and uses thereof Antibody to latent membrane proteins and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 35/12 (2006.01) A61K 39/245 (2006.01) A61K 39/395 (2006.01) A61P 31/12 (2006.01) C07K 14/05 (2006.01) C07K 16/08 (2006.01) C07K 16/32 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2468259

The present invention provides antibodies and antibody fragments directed against extracellular domains of the EBV LMP proteins, including LMP1, LMP2A and LMP2B. The invention also provides methods of treating EBV-associated malignancies using these LMP specific antibodies.

L'invention concerne des anticorps et des fragments d'anticorps dirigés contre les domaines extracellulaires des protéines EBV et LMP, parmi lesquelles LMP1, LMP2A et LMP2B. La présente invention concerne également des méthodes permettant de traiter des malignités associées aux protéines EBV à l'aide de ces anticorps propres aux LMP.

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