Inhibition of behab cleavage and primary central nervous...

Details Inhibition of behab cleavage and primary central nervous... Inhibition of behab cleavage and primary central nervous...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C12N 1/20 (2006.01) C12N 15/63 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2452518

The present invention relates to primary CNS tumors and provides useful compositions and methods for reducing tumor volume and increasing the length of survival in mammals with primary CNS tumors, thereby providing a treatment for primary CNS tumors. The invention also relates to methods of identifying compounds for reducing tumor volume and increasing animal survival, which therefore relate to treating primary CNS tumors.

L'invention concerne des tumeurs CNS primaires et permet d'obtenir des compositions et des procédés utiles pour la réduction du volume des tumeurs et l'accroissement de la durée de survie chez des mammifères atteints de tumeurs CNS, fournissant ainsi un traitement des tumeurs CNS. L'invention concerne également des procédés d'identification de composés permettant de réduire le volume des tumeurs et d'accroître la survie animale et ayant trait, de ce fait, au traitement des tumeurs CNS primaires.

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