Promotion of cell differentiation by initially passaged cells

Details Promotion of cell differentiation by initially passaged cells Promotion of cell differentiation by initially passaged cells

C - Chemistry, Metallurgy

12

N

C12N 5/071 (2010.01) A61K 35/39 (2006.01) A61P 3/10 (2006.01) A61K 35/12 (2006.01)

Patent

CA 2333702

A method for inducing differentiation of less differentiated passaged cells by contacting the cells with initially passaged (P0), more differentiated cells of the same cell type. The method produces differentiated cell aggregates, such as pancreatic islet cell aggregates, which are useful for transplantation.

L'invention porte sur un procédé provoquant la différenciation de cellules ayant subi plusieurs passages moins différenciées en les mettant en contact avec des cellules du même type ayant subi initialement plusieurs passages (P0) et plus différenciées. Le procédé produit des agrégats de cellules différenciées tels que des agrégats de cellules d'îlots de Langherans utilisables pour des transplantations.

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