C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 48/00 (2006.01) C12N 7/04 (2006.01) C12N 15/861 (2006.01)
Patent
CA 2410665
The present invention provides modified bovine adenoviruses comprising a modification in a capsid protein wherein said protein is associated with adenovirus tropism and wherein said modification is associated with altered tropism. The present invention provides adenovirus vectors and host cells comprising such vectors. The present invention also provides methods of making and using such adenoviruses.
La présente invention porte sur des adénovirus bovins modifiés comprenant une modification dans une protéine capsidique. Cette protéine est associée à un tropisme d'adénovirus et la modification est associée à un tropisme modifié. Cette invention porte également sur des vecteurs d'adénovirus et des cellules hôtes comprenant ces vecteurs. La présente invention porte en outre sur des procédés de fabrication et d'utilisation des adénovirus.
Borden Ladner Gervais Llp
University Of Saskatchewan
LandOfFree
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