Use of glutamate, glutamate derivatives or metabolites,...

A - Human Necessities – 61 – K

Patent

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A61K 31/198 (2006.01) A23L 1/305 (2006.01)

Patent

CA 2467676

A method for obtaining improved bone quality in a vertebrate, including mammal and bird, the method comprising administering to a vertebrate, including mammal and bird, in a sufficient amount and/or at a sufficient rate to enable a desired effect, glutamate, glutamate derivatives or metabolites, glutamate analogues or mixtures thereof. Also contemplated is a method for modulating bone quality in a vertebrate, including mammal and bird, comprising administering to the vertebrate, including mammal and bird, in the need thereof, glutamate, glutamate derivatives or metabolites, glutamate analogues or mixtures thereof, for modulating the bone quality as well as a compositions for use in treatment.

L'invention concerne un procédé permettant d'améliorer la qualité des os chez les vertébrés, notamment les mammifères et les oiseaux. Ce procédé consiste à administrer à un vertébré, notamment un mammifère ou un oiseau, en quantité suffisante et/ou à un taux suffisant pour obtenir l'effet désiré, du glutamate, des métabolites ou des dérivés du glutamate, des analogues du glutamate ou des mélanges de ceux-ci. L'invention concerne également un procédé permettant de moduler la qualité des os chez les vertébrés, notamment les mammifères et les oiseaux. Ce procédé consiste à administrer à un vertébré, notamment un mammifère ou un oiseau, nécessitant un traitement, du glutamate, des métabolites ou des dérivés du glutamate, des analogues du glutamate ou des mélanges de ceux-ci de façon à moduler la qualité des os. L'invention concerne par ailleurs une composition à utiliser dans ce traitement.

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