Rnai potency prediction method

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) G06F 17/50 (2006.01) G06N 3/10 (2006.01)

Patent

CA 2545675

Methods for making an algorithm for the prediction of the RNAi potency of a RNAi reagent are provided. Also provided are methods for predicting the RNAi potency of a RNAi reagent and methods for inhibiting the expression of a given target gene using such an algorithm.

L'invention concerne des procédés permettant de mettre au point un algorithme pour prédire l'efficacité de l'ARNi d'un réactif ARNi. L'invention concerne également des procédés permettant de prédire l'efficacité d'un réactif ARNi, ainsi que des procédés permettant d'inhiber l'expression d'un gène cible donné, à l'aide d'un tel algorithme.

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