C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 317/62 (2006.01) A61K 31/335 (2006.01) A61K 31/41 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07C 311/29 (2006.01) C07C 311/41 (2006.01) C07D 235/06 (2006.01) C07D 235/30 (2006.01) C07D 235/32 (2006.01) C07D 249/18 (2006.01) C07D 263/58 (2006.01) C07D 277/62 (2006.01) C07D 277/82 (2006.01) C07D 303/36 (2006.01) C07D 307/79 (2006.01) C07D 319/18 (2006.01) C07D 327/04 (2006.01)
Patent
CA 2215066
Selected sulfonylalkanoylamino hydroxyethylamine sulfonamide compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to such retroviral protease inhibitors and, more particularly, relates to selected novel compounds, composition and method for inhibiting retroviral proteases, such as human immunodeficiency virus (HIV) protease, prophylactically preventing retroviral infection or the spread of a retrovirus, and treatment of a retroviral infection.
L'invention porte sur des composés sélectionnés du type sulfonylalcanoylamino hydroxyéthylamino sulfonamide de formule (I) s'avérant efficaces comme inhibiteurs de protéases de rétrovirus et notamment de celle du VIH, et plus particulièrement sur de nouveaux composés, compositions et procédés d'inhibition des protéases de rétrovirus telle que celle du VIH, de prévention prophylactique et de traitement des infections rétrovirales, et de prévention de la dissémination des rétrovirus.
Decrescenzo Gary A.
Devadas Balekudru
Freskos John N.
Getman Daniel P.
Mcdonald Joseph J.
G.d. Searle & Co.
G.d. Searle Llc
Sim & Mcburney
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