Probe conjugation to increase multiplex binding motif...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2513125

A kit for capturing a target includes a probe and a capture primer adapted to bond to the probe to form a primed probe complex pursuant to a Watson-Crick complementary base interaction or a homologous base interaction binding motif, wherein the primed probe complex is adapted to capture the target by binding the probe to the target pursuant to the binding motif of the primed probe complex. A corresponding method for capturing a target is also disclosed.

La présente invention concerne une trousse permettant de capturer une cible, qui comprend une sonde et une amorce de capture apte à se lier à la sonde afin de former un complexe sonde-amorce reposant sur une interaction des bases complémentaires Watson-Crick ou sur un motif de liaison par interaction des bases homologues, le complexe sonde-amorce étant apte à capturer la cible en liant la sonde à la cible selon le motif de liaison du complexe sonde-amorce. L'invention se rapporte également à un procédé correspondant de capture de cible.

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