Stabilized pediatric suspension of carisbamate

A - Human Necessities – 61 – K

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A61K 9/00 (2006.01) A61K 31/27 (2006.01)

Patent

CA 2703971

The present invention provides a stabilized pharmaceutical suspension of carisbamate for pediatric and adult use. More particularly, the suspension is stabilized with hypromellose (HPMC) to prevent crystal growth of the suspended particles and to prevent re-crystallization of the drug product with change in polymorphic form.

La présente invention concerne une suspension pharmaceutique stabilisée de carisbamate destinée à être utilisée pour des enfants ou des adultes. Plus particulièrement, on stabilise ladite suspension avec de l'hypromellose (HPMC), en vue de prévenir la croissance cristalline des particules en suspension et la recristallisation du produit de médicament avec un changement de la forme polymorphe.

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