Quinone compound, its production and use

Details Quinone compound, its production and use Quinone compound, its production and use

C - Chemistry, Metallurgy

07

D

C07D 211/14 (2006.01) A61K 31/13 (2006.01) A61K 31/395 (2006.01) A61K 31/445 (2006.01) A61K 31/535 (2006.01) C07C 225/24 (2006.01) C07D 205/02 (2006.01) C07D 207/27 (2006.01) C07D 211/76 (2006.01) C07D 295/116 (2006.01)

Patent

CA 2227985

A compound of formula (I), wherein R1, R2 and R3 independently represent H, an optionally acylated hydroxyl group, an optionally substituted amino group, an optionally substituted alkoxy group or an optionally substituted hydrocarbon group, or R2 and R3 my form an optionally substituted hydrocarbon ring; R4 represents an alkyl group; R5 represents an optionally substituted hydroxyl group; R6 and R7 independently represent an optionally substituted hydrocarbon group or R6 and R7 form an optionally substituted ring; m represents 1 or 2; and n represents an integer of 1 to 5; or a hydroquinone derivative or a salt thereof has lipoperoxide formation inhibitory effect and is useful as a medicine for treating or preventing central nervous system disorders, diseases in the circulatory system, etc.

Composé de la formule (I), dans laquelle R?1¿, R?2¿ et R?3¿ représentent indépendamment H, un groupe hydroxyle facultativement acylé, un groupe amino facultativement substitué, un groupe alkoxy facultativement substitué ou un groupe hydrocarbure facultativement substitué, ou R?2¿ et R?3¿ peuvent former un cycle hydrocarbure facultativement substitué; R?4¿ représente un groupe alkyle; R?5¿ représente un groupe hydroxyle facultativement substitué; R?6¿ et R?7¿ représentent indépendamment un groupe hydrocarbure facultativement substitué ou R?6¿ et R?7¿ forment un cycle facultativement substitué; m représente 1 ou 2 et n représente un entier de 1 à 5; ou dérivé d'hydroquinone ou sel de ce dérivé, qui exerce un effet inhibiteur de la formation de lipopéroxyde et se révèle utile comme médicament pour le traitement ou la prévention des affections du système nerveux central, des maladies du système circulatoire, etc.

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