C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/575 (2006.01) A61K 38/22 (2006.01)
Patent
CA 2687602
The present invention relates to novel peptides that are highly biologically and pharmacologically active as therapeutic agents for the treatment of numerous lung diseases or lung and/or bronchi related diseases, especially chronic obstructive pulmonary disease (COPD), cystic fibrosis (CF), and Bronchiolitis obliterans (BO). The synthetic peptides according to the invention are derivatives of vasoactive intestinal peptide (VIP) and show enhanced physical, pharmacological and biological/therapeutic properties compared to VIP.
La présente invention porte sur de nouveaux peptides qui possèdent une forte activité biologique et pharmacologique en tant qu'agents thérapeutiques pour le traitement de nombreuses maladies pulmonaires ou maladies liées aux poumons et/ou aux bronches, notamment la broncopneumopathie chronique obstructive (COPD), la fibrose kystique (CF) et la bronchiolite oblitérante (BO). Les peptides synthétiques selon l'invention sont des dérivés de peptide intestinal vaso-actif (VIP) et présentent des propriétés physiques, pharmacologiques et biologiques/thérapeutiques améliorées par comparaison avec le VIP.
Goudreau Gage Dubuc
Res International Sarl
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