Pyrrolidines which inhibit camp-specific pde

Details Pyrrolidines which inhibit camp-specific pde Pyrrolidines which inhibit camp-specific pde

C - Chemistry, Metallurgy

07

D

C07D 207/09 (2006.01) A61K 31/40 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2395173

Novel compounds (II) that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed. R1-R7, R10 and R12 are as in the application.

L'invention porte sur de nouveaux composés (II) qui sont des inhibiteurs puissants et sélectifs de PDE4, ainsi que sur leurs procédés de fabrication. L'invention porte également sur l'utilisation de ces composés dans le traitement des maladies inflammatoires et autres maladies générant des taux élevés de cytokines, et sur les troubles du système nerveux central (CNS). Dans la formule (II), R?1¿ à R?7¿, R?10¿ et R?12¿ sont tels que définis dans la demande.

Affiliated with

Also associated with

Rating

Pyrrolidines which inhibit camp-specific pde does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pyrrolidines which inhibit camp-specific pde, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pyrrolidines which inhibit camp-specific pde will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1979109