Nucleic acids and corresponding proteins entitled 273p4b7...

Details Nucleic acids and corresponding proteins entitled 273p4b7... Nucleic acids and corresponding proteins entitled 273p4b7...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 35/14 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61K 38/46 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 5/12 (2006.01) C12N 15/11 (2006.01) C12N 15/13 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) A61K 3

Patent

CA 2493928

A novel gene 273P487 and its encoded protein, and variants thereof, are described wherein 273P487 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 273P4B7 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 273P487 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 273P4B7 can be used in active or passive immunization.

L'invention concerne un nouveau gène 273P487 et la protéine qu'il code, ainsi que ses variants. Ledit gène 273P487 présente une expression spécifique aux tissus dans un tissu adulte normal et est exprimé de manière aberrante dans les cancers listés dans le tableau I. Par conséquent, le gène 273P4B7 fournit une cible diagnostique, prognostique, prophylactique et/ou thérapeutique pour le cancer. Ledit gène 273P487 ou un de ses fragments ou la protéine qu'il code ou des variants ou un de leurs fragments peuvent être utilisés pour déclencher une réponse immunitaire humorale ou cellulaire. Selon l'invention, des anticorps ou des lymphocytes T réagissant au gène 273P4B7 peuvent être utilisés dans le cadre d'une immunisation active ou passive.

Affiliated with

Also associated with

Rating

Nucleic acids and corresponding proteins entitled 273p4b7... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acids and corresponding proteins entitled 273p4b7..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acids and corresponding proteins entitled 273p4b7... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1979148