Pharmacological uses of optically pure (+)-bupropion

Details Pharmacological uses of optically pure (+)-bupropion Pharmacological uses of optically pure (+)-bupropion

A - Human Necessities

61

K

A61K 31/135 (2006.01) A61K 9/20 (2006.01) A61K 31/137 (2006.01)

Patent

CA 2318921

Methods and compositions are disclosed utilizing the optically pure (+)-isomer of bupropion to assist in smoking cessation, for treating smoking and nicotine addiction, and for treating pain, including, but not limited to, chronic pain, neuropathetic pain, and reflex sympathetic dystrophy, and other disorders such as narcolepsy, chronic fatigue syndrome, fibromyalgia, seasonal affective disorder and premenstrual syndrome, while avoiding adverse affects associated with racemic bupropion.

La présente invention concerne des méthodes et des compositions utilisant l'isomère(+) de bupropion optiquement pur, destinés à faciliter la désaccoutumance au tabac, au traitement de la dépendance à la nicotine et au tabac, et au traitement de la douleur, y compris, mais non de façon limitative, de douleurs chroniques, de douleurs neuropathiques et d'algodystrophie sympathique réflexe, et d'autres troubles tels que la narcolepsie, le syndrome de fatigue chronique, la fibromyalgie, les troubles affectifs saisonniers et le syndrome prémenstruel, tout en évitant les effets indésirables associés au bupropion racémique.

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