Method for analysis of oligonucleotide analogs

Details Method for analysis of oligonucleotide analogs Method for analysis of oligonucleotide analogs

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2421043

Disclosed are methods for separating, detecting, quantitating and/or isolating predominantly uncharged oligonucleotide analogs, by resolving duplexes of such molecules with complementary or near-complementary DNA or charged DNA analogs. The DNA or charged analog may be labeled for detection purposes.

L'invention porte sur des procédés de séparation, détection, quantification et/ou isolement d'analogues d'oligonucléotides majoritairement non chargés, qui consiste à redissoudre les doubles de ces molécules à l'aide d'ADN complémentaire ou quasi complémentaire ou d'analogues chargés d'ADN. L'ADN ou l'analogue chargé peut être marqué à des fins de détection.

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