Pyrazolo[3,4-c]quinolines, pyrazolo[3,4-c]naphthyridines,...

Details Pyrazolo[3,4-c]quinolines, pyrazolo[3,4-c]naphthyridines,... Pyrazolo[3,4-c]quinolines, pyrazolo[3,4-c]naphthyridines,...

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01)

Patent

CA 2603063

Pyrazolo[3,4-c]quinolines, pyrazolo[4,5-c]naphthyridines, and analogs thereof, eg., 6,7,8,9-tetrahydro pyrazolo[3,4-c]quinolines, and, pharmaceutical compositions containing the compounds, intermediates, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inhibiting cytokine biosynthesis in animals and in the therapeutic or prophylactic treatment of diseases by inhibiting cytokine biosynthesis are disclosed.

Pyrazolo[3,4-c]quinolines, pyrazolo[4,5-c]naphthyridines, analogues de celles-ci, tels que 6,7,8,9-tétrahydro-pyrazolo[3,4-c]quinolines, compositions pharmaceutiques à base de ces composés, intermédiaires, procédés de fabrication de ces composés convenant, non seulement comme immunomodulateurs capables d'inhiber la biosynthèse cytokinique chez les animaux, mais aussi comme agents thérapeutiques ou prophylactiques d'affections par inhibition de la biosynthèse cytokinique.

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