Nucleic acid molecule encoding a mismatch endonuclease and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/55 (2006.01) C07H 21/04 (2006.01) C12N 9/22 (2006.01) C12N 15/63 (2006.01) C12N 15/867 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2400441

Nucleic acid molecules encoding a mismatch endonuclease and its method of use for the detection of mutations in targeted polynucleotide sequences are provided, which facilitate the localization and identification of mutations, mismatches and genetic polymorphisms.

L'invention porte sur des molécules d'acide nucléique: codant pour une endonucléase mésapariée dans des séquences ciblées de polynucléotides, et facilitant la localisation et l'identification des mutations, des mésapariements et des polymorphismes génétiques.

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