A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 9/50 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) C07K 17/00 (2006.01) A61L 27/34 (2006.01) A61L 29/08 (2006.01) A61L 31/10 (2006.01)
Patent
CA 2675972
Disclosed herein are polypeptide multilayer films wherein a therapeutic agent is covalently linked to a first layer polypeptide. An advantage of such attachment is that the linked therapeutic agent can be controllably released from the multilayer film into the environment of the film upon the addition of a suitable stimulus. An advantage of the disclosed films and methods is enablement of environmentally-stimulated release under specific conditions.
L'invention concerne des films multicouches de polypeptides caractérisés en ce qu'un agent thérapeutique est lié de façon covalente à un polypeptide de la première couche. Une telle fixation présente l'avantage de pouvoir libérer de façon contrôlable l'agent thérapeutique lié, du film multicouche vers l'environnement du film, lors de l'ajout d'un stimulus approprié. Les films et procédés de l'invention présentent l'avantage de permettre une libération stimulée par l'environnement dans des conditions précises.
Artificial Cell Technologies Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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