C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 489/08 (2006.01)
Patent
CA 2752744
The invention provides a process for the N-alkylation of normorphinan compounds to produce N-alkyiated morphinan compounds. In particular, the process relates to the alkylation of a normorphinan compound by a carboxaldehyde in the presence of a reducing agent to form an N-alkylated morphinan.
La présente invention concerne un procédé de N-alkylation de composés normorphinanes pour produire des composés morphinanes N-alkylés. En particulier, le procédé concerne l'alkylation d'un composé normorphinane par un carboxaldéhyde en présence d'un réducteur pour former un morphinane N-alkylé.
Hudson Edmund C.
Woods Sharon
Mallinckrodt Inc.
Osler Hoskin & Harcourt Llp
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