C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/02 (2006.01) A61K 39/145 (2006.01)
Patent
CA 2741961
The present invention relates to a method for degrading host cell nucleic acids associated with a virus or a viral antigen thereof produced by cell culture, the method comprising at least two steps of nucleic acids degradation with a compound selected from i) an endonuclease and ii) a DNA alkylating agent.
La présente invention porte sur un procédé pour la dégradation d'acides nucléiques de cellule hôte associés à un virus ou un antigène viral de celui-ci produit par culture cellulaire, le procédé comprenant au moins deux étapes de dégradation d'acides nucléiques avec un composé choisi parmi i) une endonucléase et ii) un agent d'alkylation d'ADN.
Andre Bruno Rene
Champluvier Benoit Paul Suzanne
Van Der Heyden Benedicte
Glaxosmithkline Biologicals S.a.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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